Other Ingredients: Calcium carbonate, stearic acid, croscarmellose sodium, magnesium stearate, silica, and coating (hypromellose and glycerin).
Contains wheat & soy.
What's Inside & Why
A plain-language breakdown of each blend and standout ingredient.
Replenisher
Amino Blend
6 g per serving — Glycine, L-leucine, L-glutamine, L-valine, L-isoleucine
These essential and conditionally-essential amino acids are the building blocks for muscle protein synthesis. BCAAs like L-leucine, L-valine, and L-isoleucine are metabolized directly in muscle tissue and have been shown to reduce exercise-induced fatigue, limit muscle breakdown, and support recovery—particularly important when caloric intake is reduced on a GLP-1 regimen.
Replenisher
Hydrolyzed Collagen
2.5 g per serving — Bovine collagen peptides, Type I & III
Hydrolyzed (pre-digested) collagen peptides provide the amino acid profile—especially glycine, proline, and hydroxyproline—that the body uses to synthesize new collagen. Type I & III collagen supports skin elasticity, joint integrity, and connective tissue health. Rapid weight loss can accelerate collagen loss; this inclusion directly addresses that risk.
Replenisher
Prebiotic Fiber Blend
2 g per serving — Resistant dextrin (Fiberest™), Chicory root extract
Resistant dextrin and inulin-type fructans from chicory root are selectively fermented by beneficial gut bacteria such as Bifidobacteria and Lactobacillus. This fermentation increases short-chain fatty acid production, which supports a healthy gut lining and regulates digestive motility—a common concern for people using GLP-1 medications.
Replenisher
Electrolyte Blend
811 mg per serving — Magnesium citrate, potassium citrate, sea salt
GLP-1 users often experience reduced food and fluid intake, increasing the risk of electrolyte imbalance. This blend supplies sodium, potassium, and magnesium in highly bioavailable citrate forms. Together they maintain fluid balance, support muscle contraction and nerve signaling, and help prevent the fatigue and cramping associated with electrolyte depletion.
Replenisher
Green Tea Extract
100 mg per serving — Standardized to 50% caffeine
Green tea extract provides both caffeine and EGCG (epigallocatechin gallate), a potent antioxidant catechin. The caffeine fraction contributes to sustained energy and mental clarity, while EGCG has been studied for its role in supporting metabolic rate, fat oxidation, and cardiovascular health. The extract is standardized to ensure consistent, effective delivery.
Replenisher
Hyaluronic Acid
10 mg per serving — From sodium hyaluronate
Hyaluronic acid is a naturally occurring molecule found in skin, eyes, and joints that retains water to keep tissues lubricated and plump. When taken orally, supplemental hyaluronic acid has been shown to improve skin hydration, reduce fine lines, and support joint comfort. Skin changes are a frequently reported side effect of GLP-1-driven weight loss—this ingredient directly targets that outcome.
Vitamin B6 (pyridoxine) is a coenzyme involved in over 100 enzymatic reactions, including protein and glucose metabolism, neurotransmitter synthesis (serotonin, dopamine, GABA), and immune function. Deficiency is common in restricted diets and correlates with fatigue and mood disturbances. The active form used—pyridoxine hydrochloride—is well-absorbed and stable.
Both Products
Vitamin B12
Both products: 100 mcg (4,167% DV) — as methylcobalamin
Methylcobalamin is the bioactive, methylated form of vitamin B12, readily utilized by the body without requiring conversion. B12 is essential for red blood cell formation, DNA synthesis, and the maintenance of myelin—the protective sheath around nerve fibers. GLP-1 receptor agonists and reduced protein intake can both impair B12 status; the high dose here ensures sufficiency.
Frequently Asked Questions
Supplement FAQReplenisher Powder FAQ
Collapsible content
Why did you decide to create Replenza™?
Replenza™ physician-developed formulas have been built to provide nutritional support to those on a GLP-1 weight loss journey. The products help to fill the vitamin and minerals gap and support adequate intake.
Is Replenza™ safe?
Replenza™ is composed of ingredients like Vitamin B12, Vitamin D, and Probiotics that the body needs to function optimally. Our physician developed formulation has been third-party lab tested and manufactured in a GMP compliant facility to ensure the highest safety for its consumers. However, we always suggest you consult your physician.
What makes Replenza™ Nutritional Supplement different from a daily multi-vitamin?
Replenza™ Nutritional Supplement is specifically formulated to meet the nutritional needs of individuals on a GLP 1 weight loss journey. For example it has Vitamin B12, Vitamin D and other important vitamins and minerals. Unlike most multi-vitamins, Replenza™ contains digestive enzymes to assist in the digestion, metabolism and absorption of various nutrients.
Why should I take this multi-vitamin vs. another brand?
Replenza™ Nutritional Supplement is specifically formulated to meet the nutritional needs of individuals on a GLP 1 weight loss journey. For example it has Vitamin B12, Vitamin D and other important vitamins and minerals. Unlike most multi-vitamins, Replenza™ contains digestive enzymes to assist in the digestion, metabolism and absorption of various nutrients.
Will the effects of Replenza™ plateau after a certain amount of time?
Replenza™ is designed to help supplement your body while on GLP-1 or any caloric deficit diet and we recommend you continue supporting your body’s natural needs for as long as you are taking a GLP-1. Replenza™ was created to support and “help fill in the gaps” if you are not able to consume all the proper nutrients your body needs through food. Combining our products with a balanced diet will produce the best results.
How long until I start feeling the effects of Replenza™?
It is recommended to take Replenza™ for a minimum of 30 days to begin to experience the benefits. It also depends on an individual’s baseline. If there is a vitamin deficiency present it can take 3 months to remedy. In addition, some deficiencies may take therapeutic doses prescribed by a doctor if levels remain low.
Does Replenza™ cause side effects like a GLP-1 receptor agonist or semaglutide?
Replenza™ is designed to provide you with the vitamins and minerals you may be lacking in your diet while on a GLP-1 weight loss journey.
Our products contain ingredients to help people meet their nutritional needs.
How long should Replenza™ be taken?
Replenza™ products should be taken daily and can be taken for as long as you experience benefits. If you have further questions, please consult with your healthcare provider.
Can I take Replenza™ while on a GLP-1 receptor agonist or semaglutide?
Absolutely! Our line is specifically formulated for those on a GLP-1 journey. Our products were developed to help your body stay nourished while on your weight loss journey.
How long until I start feeling the effects of Replenza™?
The effects will vary from person to person. It is recommended to take Replenza™ for a minimum of 30 days to begin to experience the benefits. It also depends on an individual’s baseline. If there is a vitamin deficiency present, it can take 3 months to remedy. In addition, some deficiencies may take therapeutic doses prescribed by a doctor if levels remain low.
What lifestyle habits should someone adopt to maximize the benefit of taking Replenza™?
A balanced diet filled with colorful fruits, vegetables, lean protein, healthy fats and a wide range of dietary fibers supports a healthy gut microbiome. It’s also important to maintain healthy stress levels and remain physically active. In addition, following a nutritious diet and regular exercise plays an integral part.
Collapsible content
Why did you decide to create Replenza™?
Replenza™ physician-developed formulas have been built to provide nutritional support to those on a GLP-1 weight loss journey. The products help to fill the vitamin and minerals gap and support adequate intake.
Is Replenza™ safe?
Replenza™ is composed of ingredients like Vitamin B12, Vitamin D, and Probiotics that the body needs to function optimally. Our physician developed formulation has been third-party lab tested and manufactured in a GMP compliant facility to ensure the highest safety for its consumers. However, we always suggest you consult your physician.
What makes Replenza™ Replenisher different from regular Amino Acids?
Our formula contains a balance of Branched Chain Amino Acids (BCAAs) which may support muscle recovery.
Will the effects of Replenza™ plateau after a certain amount of time?
Replenza™ is designed to help supplement your body while on GLP-1 or any caloric deficit diet and we recommend you continue supporting your body’s natural needs for as long as you are taking a GLP-1. Replenza™ was created to support and “help fill in the gaps” if you are not able to consume all the proper nutrients your body needs through food. Combining our products with a balanced diet will produce the best results.
How long until I start feeling the effects of Replenza™?
It is recommended to take Replenza™ for a minimum of 30 days to begin to experience the benefits. It also depends on an individual’s baseline. If there is a vitamin deficiency present it can take 3 months to remedy. In addition, some deficiencies may take therapeutic doses prescribed by a doctor if levels remain low.
Does Replenza™ cause side effects like a GLP-1 receptor agonist or semaglutide?
Replenza™ is designed to provide you with the vitamins and minerals you may be lacking in your diet while on a GLP-1 weight loss journey.
Our products contain ingredients to help people meet their nutritional needs.
Will I be able to sleep if I take Replenza™ Replenisher at night?
Replenza™ contains green tea extract, which is a source of caffeine (100mg). In individuals where sleep is affected by caffeine, it is recommended to take the Replenish earlier in the day.
Can I skip meals and just have Replenza™ Replenisher?
No. Our products do not replace food in your diet. Using the Replenza™ Replenish as a part of the base of a smoothie is an excellent way to incorporate our product.
Supplement will provide additional vitamin and minerals if you are not getting enough from your diet.
Can I take Replenza™ while on a GLP-1 receptor agonist or semaglutide?
Absolutely! Our line is specifically formulated for those on a GLP-1 journey. Our products were developed to help your body stay nourished while on your weight loss journey.
When should I take Replenza™ Replenisher?
Most supplements are best absorbed and tolerated when consumed with a meal or snack. We recommend taking Replenza™ in the 1st half of the day since it does contain some caffeine.
How long until I start feeling the effects of Replenza™?
The effects will vary from person to person. It is recommended to take Replenza™ for a minimum of 30 days to begin to experience the benefits. It also depends on an individual’s baseline. If there is a vitamin deficiency present, it can take 3 months to remedy. In addition, some deficiencies may take therapeutic doses prescribed by a doctor if levels remain low.
What lifestyle habits should someone adopt to maximize the benefit of taking Replenza™?
A balanced diet filled with colorful fruits, vegetables, lean protein, healthy fats and a wide range of dietary fibers supports a healthy gut microbiome. It’s also important to maintain healthy stress levels and remain physically active. In addition, following a nutritious diet and regular exercise plays an integral part.
Ready to Replenish?
Replenza™ is NSF Certified, GMP Compliant, and made in the USA. Shop the full system and support your GLP-1 journey with science-backed nutrition.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular health care provider.
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